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KMID : 0358419960390030539
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Korean Journal of Obstetrics and Gynecology
1996 Volume.39 No. 3 p.539 ~ p.544
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Pregnancy after Preimplantation Diagnosis for a Chromosomal Translocation by FISH in Embryos Obtained after Intracytoplasmi Sperm Injection
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이숙환
이혜경/김언경/박성은/엄기붕/고정재/차광열
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Abstract
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Fluorescent detection of in situ hybridization(FISH) with whole chromosome painting probe(chromosome 2 and 6) has used to assess the use of this method for preimplantation diagnosis of the carrier of a balanced translocation t(2 ; 6)(p13 ; p21)
which
has repeatedly led to spontaneous abortions. Interphase nuclei have been analyzed and four embryos with 5 green/red signals each for the chromosome 2 and 6 were transferred and a pregnancy resulted.
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